Reactivity And Selectivity in Nucleophilic Aromatic Substitution Reactions Using Sulfur-Based Nucleophiles

Abstract: A new category of nucleophilic aromatic substitutions, short for “conducted” SNAr instead of the more conventional “two-step” SNAr processes, has recently emerged as a result of advances in computational and experimental chemistry. In contrast to conventional SNAr reactions, which need substitutions that remove electrons, which greatly stimulate aromatic ring, concerted routes do not necessitate such groups. Organic chemistry revolves on substitution processes using aromatic rings. Some more processes that are regularly found include electrophilic aromatic substitution, SNAr nucleophilic aromatic substitution, SNArH, and vicarious nucleophilic, which are separate yet similar. The traditional stepwise method was considered the common mechanism for aromatic nucleophilic substitutions, whereas concerted nucleophilic substitutions were very unusual.

Keywords: Nucleophilic, Aromatic, Substitution, Reactions, and Sulfur.


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